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Peter Attia Intro
0:39 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter Introduces Matt Kaeberlein
2:49 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter & Matt Frequently Exchange Nutrition & Longevity Papers Over Email
1:16 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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With Minimal Variables, Rapamycin Dosing Is Complicated; Now Imagine Nutrition...
3:26 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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When Advising a Patient on Nutrition, Peter Attia Asks These 3 Questions
2:37 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt Kaeberlein Has Trust Problems With Nutritionists & Diet Gurus
2:01 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter Recommends Taking an 80/20 Approach to Nutrition; Focus Extra Effort on Exercise
2:44 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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In Nearly All Organisms Studied, Caloric Restriction Slows Aging
3:27 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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A Criticism of the Caloric Restriction Literature: Unlike Humans, Mice Typically Die of Cancer
3:07 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt Kaeberlein Isn't Convinced Epigenetic Clocks Adequately Measure Biological Age
3:02 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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No Data Supports the Fact That Reversing the Epigenome Reverses Aging
1:05 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt Thinks the Yamanaka Factor/Epigenome Data Is Exaggerated; No One's Reversed Aging... Yet
3:48 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Are Epigenetic Changes Aging's Primary Cause? Matt Kaeberlein Is Skeptical
5:08 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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How Does Restoring the Epigenome Affect Mitochondria, Heart, & Brain Function?
3:42 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Misleading the General Public That We're Close to Reversing Aging Is Problematic
2:30 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt Kaeberlein: Don't Expect Lifespan-Increasing FDA-Approved Treatments in the Next 20 Years
3:30 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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50% of Exercise's Benefits Are Captured Going From Nothing to 15 MET Hours/Week
1:48 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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In Animal Studies, Caloric Restriction Impairs Immune Function
2:48 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Calorically Restricted Mice Maintain Muscle Function Proportionate to Body Weight
3:03 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Caloric Restriction-Driven Weight Loss Decreases Bone Mineral Density
2:15 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter & Matt React to the Wisconsin & Bethesda Rhesus Monkey Caloric Restriction Studies
8:45 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Analyzing Caloric Restriction Studies: Humans & Rhesus Monkeys Have Different Energy Expenditures
3:17 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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There's No Reason to Think a Hunter-Gatherer Diet Is Optimal for Longevity
2:39 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Food Quality & Taste Is Dramatically Different Than 50 Years Ago
1:03 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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The Grandmother Test: Foods on the Grocery Store Perimeter > Packaged Junk
1:34 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt's 2021 Paper Reviewed Popular Anti-Aging Diets: Caloric Restriction, IF, Keto, & More
7:15 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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In Mice, Caloric Restriction's Lifespan Benefits Result from Calorie Reduction & Fasting
4:16 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Because of Insulin Sensitivity, Early > Late Time-Restricted Feeding Windows
2:16 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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In Mice, Intermittent Ketogenic Diets Increase Lifespan & Healthspan
2:05 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Despite Potential Lifespan Benefits, Caloric Restriction Has Psychological Consequences in Humans
2:55 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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In Mice, Caloric Restriction Appears to Increase Lifespan Most When Started Early
1:41 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Calorie Restriction's Lifespan-Boosting Effects Are Greatest When Started Early in Mice
5:34 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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A 2009 Paper Discovered Late-Life Rapamycin Supplementation Increases Lifespan in Mice
3:54 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Rapamycin from Compounding Pharmacies Has Lower Bioavailability
1:03 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter Attia Consumes 1g of Protein Per Pound of Body Weight Spread Into 4 Buckets
2:32 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Protein Restriction Downregulates mTOR & Secretes FGF21 in Mice, Increasing Lifespan
4:46 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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The mTOR Spike from Branched-Chain Amino Acids Is Short-Lived
2:53 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt Hasn't Witnessed Rapamycin Causing Muscle Loss in Mice, Dogs, or Humans
1:54 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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There Are Multiple Diet Paths to Longevity — Even Ones Consisting of 40% Protein
1:49 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Protein-Rich Diets Increase Muscle Mass, Which Is Essential for Glucose Homeostasis
3:41 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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For Reducing Mortality Risk, Valter Longo Recommends a Low-Protein Diet Until Age 65
5:24 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Mutations That Reduce Growth Hormone Signaling Increase Lifespan in Mice
3:47 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Why Peter Attia Refuses to Put Patients on Growth Hormone
1:51 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Peter & Matt Are Surprised Exogenous Growth Hormone Doesn't Present Clear Detriments
1:31 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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The IGF-1/Longevity Story Is More Complicated Than 'IFG-1 Is Bad'
3:05 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Mutations That Lower Growth Hormone Signaling Reduce Cancer Risk
2:48 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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All Things Equal, High Growth Hormone & IGF-1 Signaling Increases Cancer Risk
3:28 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Matt & Peter Outro
1:44 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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AD: Peter's Podcast Membership Program
1:15 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Connect With Peter Online
0:10 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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Disclaimer
1:21 ·
How nutrition impacts longevity |
Matt Kaeberlein
, Ph.
D
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