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Andrew Huberman Intro (Part I)

1:32 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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In the Brain, Every Bit of Pleasure-Seeking Is Balanced By a Surge of Pain

4:02 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Andrew Huberman Is Helping a 21-Year-Old Man Reset His Pleasure-Pain Pathway

1:33 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Disclaimer

0:13 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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AD: InsideTracker

1:16 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Athletic Greens

1:17 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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AD: Belcampo

1:20 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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The Difference Between Bipolar & Major Depression

1:06 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Andrew Huberman Intro (Part II)

2:00 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Major Depression Impacts 5% of People; It's the #4 Cause of Disability

0:54 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Language Is the Primary Diagnosis Tool for Depression

0:50 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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The Hallmarks of Major Depression: Grief, Crying, Anhedonia, Guilt, & Anti-Self Confabulation

5:31 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Vegetative Tendencies Are a Common Symptom of Major Depression

1:33 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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People With Major Depression Have Disrupted Sleep Architectures

0:52 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Decreased Appetite Is a Common Symptom of Major Depression

0:57 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Major Depression Often Causes Sleep, Appetite, & Hormonal Disruptions

2:12 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Tricyclic Antidepressants & MAO Inhibitors Increase Norepinephrine, Reducing Depressive Symptoms

2:53 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Defects in the Brain's Dopamine Pathway Are a Key Driver of Depression

1:38 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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SSRIs Like Prozac & Zoloft Prevent the Clearance of Serotonin from Synapses

2:07 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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SSRIs Have Many Adverse Side Effects & Don't Work in 1/3 People

0:52 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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SSRIs May Reduce Depressive Symptoms Through Neuroplasticity & Neurogenesis

2:08 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Variations in Norepinephrine, Dopamine, & Serotonin Determine Depressive Symptoms

2:31 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Physical & Emotional Pain Systems Are Linked; Drugs That Treat One Often Treat the Other

1:26 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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The Chemistry Underlying Depression: Dopamine, Norepinephrine, & Serotonin

0:56 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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20% of People With Major Depression Have Low Thyroid Hormone

3:12 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Experiencing 4-5 Stressful Episodes Increases Risk for Major Depression

1:49 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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5-HTTLPR Gene Polymorphisms Increase Risk for Stress-Caused Major Depression

2:21 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Identical Twins Illustrate Depression's Strong Genetic Component

1:14 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Understanding Biological Mechanisms Is Essential for Utilizing Depression Mitigation Tactics

2:21 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Why Depressed Individuals Have Difficulty Harnessing Exercise's Antidepressant Effects

3:17 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Excessive Inflammation Is a Primary Cause of Major Depression

3:11 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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1,000 mg of EPA Daily Reduces Depressive Symptoms

3:29 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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EPAs Reduce Inflammatory Cytokines, Facilitating Serotonin Production from Tryptophan

2:37 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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By Shuttling Kynurenine Into Muscles, Exercise Acts as an Antidepressant

1:28 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Exercise & EPA Consumption Act on the Same Biochemical Pathways as Antidepressants

2:25 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Supplementing With 1,000 mg EPA Daily Helps Andrew Reduce Depressive Symptoms

2:14 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Creatine Monohydrate Supplementation Improves Physical Performance & Mood

2:52 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Creatine Supplementation Improves Mood By Altering NMDA Receptor Function

6:02 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Ketamine & PCP Treat Depression By Acting on Layer 5 Neurons & Blocking NMDA Receptors

7:03 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Ketamine Offsets Depressive Symptoms By Increasing Spines on Prefrontal Cortex Neurons

3:03 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Ketamine Treats Depression By Helping Users Realize 'I Am Not My Emotions'

3:15 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Andrew Summarizes a 2020 Study Which Utilized Psilocybin for Treating Major Depression

5:32 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Regardless of Experience Quality, Psilocybin Relieves Depressive Symptoms in Clinical Studies

3:44 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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For Reducing Depressive Symptoms, Microdosing Psilocybin Pales in Comparison to High Doses

3:03 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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MDMA Is More Useful for Treating Trauma Than Depression

0:42 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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The Ketogenic Diet Reduces Mood Swings in Bipolar Depression Patients

2:38 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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By Increasing GABA Transmission, the Ketogenic Diet Treats Epilepsy

3:03 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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People With Major Depression May Benefit from a Ketogenic Diet

2:12 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Andrew Huberman's 5-Minute Summary: How to Treat & Mitigate Depression

5:21 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Andrew Huberman Outro (Part I)

0:53 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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Thorne

0:43 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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0:14 · Understanding & Conquering Depression | Episode 34 - Andrew Hubermanview episode

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