The internet is not well made for protecting our mental health. In many ways, it is a hellscape for our mental health.

Human psychology is dis-evolved, improperly evolved, for a world where we are getting our sense of self from a screen, from a phone, where we're open to the opinion of anonymous hordes. We're not built for that ... We're just not meant to live through screens.

One trial found that people on Ozempic went on longer walks. There's a Morgan Stanley survey that found that patients on GLP-1s ate 60% less candy and 40% more vegetables. It seems to reduce smoking for smoking addicts, gambling for gambling addicts, and even for some compulsive nail-biting.

The physical world has gotten a little bit safer, but the emotional experience of teenagers has gotten worse—and I think it's basically gotten worse because of phones.

The erosion of the mainstream across categories—news and politics and celebrity media—has turned culture into a portfolio of cults, and that's made it really hard for people to talk to and understand each other.

We live in a world where anxiety and mental health issues have been destigmatized. It used to be shameful to say that you had depression or anxiety ... Today, there's a way in which mental health issues, anxiety and depression, have become kind of like identities—people talk about them openly and sometimes even proudly on social media.

She said, 'You can see how the Internet and the way the Internet talks about mental health might be really bad for our mental health, and we need a better way of talking about anxiety and depression on the Internet if we actually want to dispel this stuff rather than just marinate in it.'

If you look at the official data from the CDC, the youth behavior risk survey, teenage anxiety, sadness, hopelessness—it's just going up and up and up.

Most people think of these drugs as weight loss drugs. And I am on the train of no, you should actually maybe think of them as psychiatric drugs that work through your gut.

One of the big problems of these drugs is that with really fast weight loss, people tend to lose both fat and muscle. And for older people, really for anyone, muscle retention is really important...

Because GLP-1 drugs have been around for 10 or 15 years for diabetics, people taking them now are not the guinea pigs. People who were taking them in, say, 2006-2008, they were the real guinea pigs.

Mahomes clearly has the best start to a career in the history of NFL quarterbacks. He combines the physical talents of Aaron Rodgers with the regular season statistical achievements of Peyton Manning with the postseason statistical achievements of Tom Brady. And we've never seen anyone do all of this the same time.

If you stop taking [Ozempic], you tend to not still enjoy the benefits. It's like statins. It's a drug that you do seemingly have to take for the rest of your life. A lot of people are going to be really uncomfortable taking a drug like this for the rest of their life.

Everywhere I look in media, I'm like, I see more and more cults. The first place I started to feel like everything is a cult is in news media ... News media, to me, is clearly becoming more cult-like.